A novel method to identify cooperative functional modules: study of module coordination in the Saccharomyces cerevisiae cell cycle
2011
New Method for Studying Gene Cooperation in Yeast Cell Cycle
Sample size: 101
publication
Evidence: high
Author Information
Author(s): Hsu Jeh-Ting, Peng Chien-Hua, Hsieh Wen-Ping, Lan Chung-Yu, Tang Chuan Yi
Primary Institution: National Tsing Hua University
Hypothesis
Can a new method identify cooperative functional modules in the yeast cell cycle?
Conclusion
The study successfully identified 101 cooperative module associations that are crucial for understanding the yeast cell cycle.
Supporting Evidence
- The method identified 101 cooperative module associations among 82 modules.
- The study established a cell cycle-specific cooperative module network.
- The identified module pairs cover pathways essential to the cell cycle.
Takeaway
The researchers found a way to see how different groups of genes work together during the yeast cell cycle, helping us understand how cells grow and divide.
Methodology
The study used a weighted physical interaction network to identify cooperative module pairs and their correlated genes.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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