Proposal for a standard representation of two-dimensional gel electrophoresis data
2003
Standard Representation of Two-Dimensional Gel Electrophoresis Data
publication
Evidence: moderate
Author Information
Author(s): Andrew Jones, Jonathan Wastling, Ela Hunt
Primary Institution: University of Glasgow
Hypothesis
A standard format for proteome data is required to enable the storage, exchange and subsequent re-analysis of large datasets.
Conclusion
The developed model for 2-DE data will facilitate the integration and analysis of large proteomics datasets.
Supporting Evidence
- A standard format will enable results to be verified or re-analyzed.
- The model captures details of the scanner and image produced.
- Statistical analyses performed on data can be documented.
- The model allows researchers to store data from various image analysis applications.
- Integration of proteomics data is vital for future research.
Takeaway
This study suggests that scientists need a common way to store and share protein data so they can work together better.
Methodology
The study developed a model to represent data from 2-DE experiments, including image and statistical analysis.
Limitations
The model does not include a proposal for annotation standards for mass spectrometry.
Digital Object Identifier (DOI)
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