Quality of Life in Prodromal HD: Qualitative Analyses of Discourse from Participants and Companions
2011

Quality of Life in Prodromal Huntington's Disease

Sample size: 15 publication Evidence: moderate

Author Information

Author(s): Rebecca E. Ready, Justin J. F. O'Rourke, Jane S. Paulsen

Primary Institution: The University of Massachusetts and The University of Iowa

Hypothesis

What is the quality of life for individuals in the prodromal phase of Huntington's Disease?

Conclusion

Individuals in the prodromal phase of Huntington's Disease focus more on their present quality of life rather than the past or future.

Supporting Evidence

  • Participants expressed more positive than negative feelings about their current quality of life.
  • Spirituality was discussed positively, while HD in others was often discussed negatively.
  • Concerns about the future varied between prodromal HD participants and their companions.

Takeaway

People who might get Huntington's Disease but don't have symptoms yet think a lot about how they feel right now, and they often have positive attitudes.

Methodology

Interviews were conducted with 9 prodromal HD participants and 6 companions, focusing on their quality of life, and the discourse was analyzed for themes.

Potential Biases

Potential bias from having a single interviewer and the unique characteristics of the sample.

Limitations

Participants may be more mentally resilient than the general population at risk for HD, limiting generalizability.

Participant Demographics

9 prodromal HD participants (4 male, average age 38.4 years, all Caucasian) and 6 companions (3 male).

Digital Object Identifier (DOI)

10.1155/2011/958439

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