Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome
Author Information
Author(s): Macdonald L, Bruce J, Scott N W, Smith W C S, Chambers W A
Primary Institution: University of Aberdeen
Hypothesis
What is the long-term outcome of post-mastectomy pain syndrome (PMPS) in breast cancer survivors?
Conclusion
Half of the women who reported PMPS in 1996 continued to experience it at a mean of 9 years after surgery.
Supporting Evidence
- Of 175 women reporting PMPS in 1996, 138 were eligible for follow-up in 2002.
- A response rate of 82% was achieved.
- 59 out of 113 women reported continued PMPS.
- Quality of life scores were significantly lower in women with persistent PMPS compared to those whose pain had resolved.
- Risk factors for persistent PMPS included younger age and heavier weight.
Takeaway
This study looked at women who had pain after breast surgery and found that many still had pain years later, but some got better.
Methodology
A cohort study design was used to assess the outcome of women who underwent mastectomy, with follow-up questionnaires assessing pain and quality of life.
Potential Biases
Potential bias due to loss of follow-up and self-reported data.
Limitations
The study had a small sample size and lacked data on preoperative quality of life and pain intensity.
Participant Demographics
Mean age of participants at follow-up was 62 years, with 85% having undergone total mastectomy.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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