Case Report of Carbachol Intoxication
Author Information
Author(s): Martin Schulz, Thomas Graefe, Klaus Stuby, Hilke Andresen, Nikolai Kupfermann, Achim Schmoldt
Primary Institution: Department of Pharmacology, University of Frankfurt
Conclusion
An 84-year-old male with carbachol intoxication experienced severe symptoms and eventually died, highlighting the risks of cholinergic poisoning.
Supporting Evidence
- The patient developed severe cholinergic symptoms after ingesting carbachol.
- Initial resuscitation efforts were successful, but the patient later died from heart failure.
- Carbachol concentrations in serum were significantly higher than expected therapeutic levels.
Takeaway
A man accidentally took too much carbachol, which made him very sick and led to his death, showing that even small mistakes with medicine can be very dangerous.
Methodology
The patient's carbachol levels in serum and urine were analyzed using HPLC-mass spectrometry.
Potential Biases
Potential bias in reporting due to the influence of media on the patient's son.
Limitations
The case is based on a single patient, limiting generalizability.
Participant Demographics
An 84-year-old male with a history of Alzheimer's disease, heart failure, and diabetes.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website