Triple-Negative Breast Cancer Characteristics and Prognosis
Author Information
Author(s): Rhee Jiyoung, Han Sae-Won, Oh Do-Youn, Kim Jee Hyun, Im Seock-Ah, Han Wonshik, Ae Park In, Noh Dong-Young, Bang Yung-Jue, Kim Tae-You
Primary Institution: Seoul National University Hospital
Hypothesis
What are the clinicopathologic characteristics and prognostic indicators of lymph node-negative triple-negative breast cancer?
Conclusion
Triple-negative breast cancer has a higher relapse rate and more aggressive characteristics compared to non-triple-negative breast cancer in node-negative cases.
Supporting Evidence
- Triple-negative breast cancer was found in 19.9% of the patients studied.
- Younger age was significantly correlated with triple-negative breast cancer.
- The relapse-free survival rate was significantly shorter for triple-negative breast cancer patients.
Takeaway
Triple-negative breast cancer is a type of breast cancer that is harder to treat and comes back more often than other types.
Methodology
Medical records were reviewed from patients with node-negative breast cancer who underwent curative surgery, evaluating clinicopathologic variables and clinical outcomes.
Limitations
Some patient records lacked immunohistochemical results, and the study had a short follow-up duration.
Participant Demographics
Majority were female (99.9%), with a median age of 47 years.
Statistical Information
P-Value
p = 0.003, p < 0.001, p = 0.004, p = 0.001
Confidence Interval
95% CI, 1.396 to 5.939; 95% CI, 1.011 to 19.986; 95% CI, 1.351 to 4.199
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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