OTC analgesics and drug interactions: clinical implications
2008
OTC Analgesics and Drug Interactions: Clinical Implications
publication
Evidence: moderate
Author Information
Author(s): Fendrick A Mark, Pan Deborah E, Johnson Grace E
Primary Institution: University of Michigan Medical Center
Hypothesis
What are the potential drug interactions associated with over-the-counter analgesics?
Conclusion
Patients should be properly counseled on the appropriate and safe use of OTC analgesics to minimize adverse effects.
Supporting Evidence
- Over 80% of American adults use at least one OTC or prescription drug each week.
- Chronic OTC analgesic use is most common in the elderly.
- Patients may not be aware of the potential for toxicity and adverse drug interactions.
Takeaway
Many people take over-the-counter pain relievers without knowing they can interact badly with other medications, so it's important to talk to a doctor about how to use them safely.
Limitations
The study does not provide specific data on the prevalence of adverse effects or interactions.
Participant Demographics
The study discusses American adults, particularly the elderly who commonly use OTC analgesics.
Digital Object Identifier (DOI)
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