Methyl 4-{[6-(4-bromophenyl)-3-oxo-2,3,4,5-tetrahydropyridazin-4-yl]methyl}benzoate
2011
Study of a New Compound with Potential Health Benefits
publication
Evidence: moderate
Author Information
Author(s): Bortoluzzi Adailton J., Souza Luciana B. P., Joussef Antônio C., Meyer Emerson
Primary Institution: Departamento de Química, UFSC
Hypothesis
The study investigates the structure of methyl 4-[6-(4-bromophenyl)-3-oxo-2,3,4,5-dihydropyridazin-4-ylmethyl]benzoate as a potential candidate for antihypertensive activity.
Conclusion
The compound exhibits a unique structure that may contribute to its biological activity.
Supporting Evidence
- The compound consists of two cyclic groups linked by a methylene spacer.
- The pyridazine ring is twisted with a dihedral angle of 17.2°.
- Intermolecular hydrogen bonds form dimers that create a one-dimensional polymeric structure.
Takeaway
Scientists looked at a new chemical compound to see if it could help lower blood pressure. They found that it has a special structure that might be useful.
Methodology
The compound was synthesized and analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website