Cefmetazole vs. Cefoxitin for Postcesarean Endometritis
Author Information
Author(s): Ashwin Chatwani, Mark Martens, David A. Grimes, Molly Chatterjee, Melvin Noah, Marion M. Stamp-Cole, Kimberly T. Perry, the Cefmetazole Study Group
Primary Institution: Temple University School of Medicine
Hypothesis
Cefmetazole is more effective than cefoxitin in treating endometritis after cesarean delivery.
Conclusion
Cefmetazole was significantly more effective than cefoxitin in treating endometritis following cesarean delivery.
Supporting Evidence
- The cure rate for cefmetazole was 89% compared to 79% for cefoxitin.
- Adverse events were similar in both treatment groups.
- Patients were followed for clinical responses and side effects.
Takeaway
This study found that cefmetazole works better than cefoxitin for treating infections after cesarean sections.
Methodology
A single-blind, multicenter, prospective, randomized study comparing cefmetazole and cefoxitin in 355 patients with endometritis after cesarean delivery.
Limitations
The study was limited to patients with endometritis after cesarean delivery and excluded those with other infections.
Participant Demographics
{"mean_age":24.3,"weight":78.3,"height":159.6,"race_distribution":{"white":16.8,"black":41.0,"oriental":0.9,"hispanic":40.0,"others":1.3}}
Statistical Information
P-Value
0.006
Statistical Significance
p<0.05
Want to read the original?
Access the complete publication on the publisher's website