Noroviruses and Gastroenteritis in Children
Author Information
Author(s): Patel Manish M., Widdowson Marc-Alain, Glass Roger I., Akazawa Kenichiro, Vinjé Jan, Parashar Umesh D.
Primary Institution: Centers for Disease Control and Prevention
Hypothesis
What is the role of noroviruses in sporadic gastroenteritis?
Conclusion
Noroviruses account for 12% of severe gastroenteritis cases among children under 5 years of age.
Supporting Evidence
- Noroviruses accounted for 12% of severe gastroenteritis cases among children under 5 years of age.
- Each year, noroviruses cause approximately 64,000 hospitalizations and 900,000 clinic visits among children in industrialized countries.
- In developing countries, noroviruses may cause up to 200,000 deaths of children under 5 years of age.
Takeaway
Noroviruses are a common cause of stomach sickness in young kids, making many of them very sick each year.
Methodology
A systematic review of studies using reverse transcription–PCR to diagnose norovirus infections in patients with diarrhea.
Potential Biases
Heterogeneity in study designs and potential publication bias.
Limitations
Limited data from developing countries and potential underestimation of disease prevalence due to diagnostic challenges.
Participant Demographics
Studies included children under 5 years of age from various income countries.
Statistical Information
Confidence Interval
95% CI 10%–15%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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