Comparative efficacy of the Cognitive Behavioral Analysis System of Psychotherapy versus Supportive Psychotherapy for early onset chronic depression: design and rationale of a multisite randomized controlled trial
2011

Comparing Two Psychotherapies for Chronic Depression

Sample size: 268 publication Evidence: moderate

Author Information

Author(s): Elisabeth Schramm, Martin Hautzinger, Ingo Zobel, Levente Kriston, Mathias Berger, Martin Härter

Primary Institution: University Medical Center Freiburg

Hypothesis

CBASP is more effective in reducing depressive symptoms than supportive psychotherapy.

Conclusion

The study aims to determine if a specific psychotherapy for chronic depression is more effective than a general supportive therapy.

Supporting Evidence

  • Chronic depression is a common and disabling disorder that often begins early in life.
  • CBASP has shown promise in previous studies for treating chronic depression.
  • Supportive psychotherapy has been used as a control in other trials but is less specific.

Takeaway

This study is trying to find out if a special kind of therapy helps people with long-term depression better than a regular supportive therapy.

Methodology

A multisite parallel-group randomized controlled trial comparing CBASP and supportive psychotherapy over 20 weeks of treatment.

Potential Biases

Potential risks include therapist allegiance and the challenge of blinding evaluators to treatment assignments.

Limitations

The study does not include a pharmacological placebo arm, which may limit the generalizability of the findings.

Participant Demographics

Participants are early-onset chronically depressed outpatients aged 18 to 65, with a DSM-IV diagnosis.

Digital Object Identifier (DOI)

10.1186/1471-244X-11-134

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