Molecular Monitoring of Hair Growth Treatments
Author Information
Author(s): Henne Sabrina K., Hochfeld Lara M., Bartmann Werner, Welss Thomas, Nöthen Markus M., Heilmann-Heimbach Stefanie
Primary Institution: Institute of Human Genetics, School of Medicine & University Hospital Bonn, University of Bonn, Bonn, Germany
Hypothesis
Can molecular monitoring provide early insights into the treatment response of hair growth stimulating agents?
Conclusion
The study demonstrates that molecular monitoring can detect treatment responses to hair growth agents as early as four days after starting treatment.
Supporting Evidence
- 91 male participants were studied to assess the effects of hair growth stimulating agents.
- 52 differentially expressed genes and 17 modulated pathways were identified after treatment.
- 23% of genes showed significant regulation after just 4 days of treatment.
Takeaway
This study looks at how we can check if hair growth treatments are working by looking at tiny bits of RNA from hair follicles, which can show changes quickly.
Methodology
Participants were assigned to treatment groups and hair follicle samples were collected for RNA sequencing before, after four days, and after six weeks of treatment.
Potential Biases
Potential conflicts of interest due to funding from Henkel AG & Co. KGaA.
Limitations
The study had a limited sample size and was exploratory in nature.
Participant Demographics
Male participants with visible signs of male-pattern hair loss or a family history of it.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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