Thyroid Lymphoma Misdiagnosed as Anaplastic Carcinoma
Author Information
Author(s): Daneshbod Yahya, Omidvari Shapour, Daneshbod Khosrow, Negahban Shahrzad, Dehghani Mehdi
Primary Institution: Dr. Daneshbod Pathology Laboratory, Shiraz, Iran
Conclusion
The study highlights the importance of immunocytochemistry in differentiating between high-grade thyroid lymphoma and anaplastic thyroid carcinoma due to their overlapping cytologic features.
Supporting Evidence
- The patient initially diagnosed with anaplastic carcinoma was found to have diffuse large B-cell lymphoma.
- Immunocytochemical studies showed positive B cell markers and negative cytokeratin.
- The tumor completely resolved after two courses of chemotherapy.
Takeaway
A 70-year-old man thought to have a serious thyroid cancer actually had a treatable type of lymphoma, showing that doctors need to be careful when diagnosing.
Methodology
Fine needle aspiration (FNA) and immunocytochemical studies were performed to differentiate between anaplastic carcinoma and lymphoma.
Limitations
The study is based on a single case report, which may not be generalizable.
Participant Demographics
One 70-year-old male patient.
Digital Object Identifier (DOI)
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