Breast cancer, psychological distress and life events among young women
2008

Breast Cancer, Psychological Distress, and Life Events Among Young Women

Sample size: 622 publication Evidence: moderate

Author Information

Author(s): Ronit Peled, Devora Carmil, Orly Siboni-Samocha, Ilana Shoham-Vardi

Primary Institution: Ben-Gurion University of the Negev

Hypothesis

Psychological distress and severe life events are risk factors for breast cancer among young women.

Conclusion

Young women who were exposed to a number of life events should be considered as a risk group for breast cancer and treated accordingly.

Supporting Evidence

  • The cases presented significantly higher scores of depression compared to the controls.
  • A significant difference was found when comparing the groups according to the cumulative number of life events.
  • Exposure to more than one life event is positively associated with breast cancer.

Takeaway

If young women go through a lot of tough life events, they might be at a higher risk for breast cancer.

Methodology

A case-control study with 622 women, using validated questionnaires to assess psychological distress and life events.

Potential Biases

The retrospective nature of the study may lead to over-reporting of stress due to knowledge of cancer diagnosis.

Limitations

The study population cannot be considered a representative sample, and the response rate among cases was low (25%).

Participant Demographics

Women aged 25-45, with 255 diagnosed with breast cancer and 367 healthy controls.

Statistical Information

P-Value

0.04

Confidence Interval

1.09–2.40

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2407-8-245

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