Impact of Animal Vaccination on Human Brucellosis in Greece
Author Information
Author(s): Eleni Jelastopulu, Christos Bikas, Chrysanthos Petropoulos, Michalis Leotsinidis
Primary Institution: Department of Public Health, Medical School, University of Patras, Patras, Greece
Hypothesis
Does the implementation of an animal brucellosis control programme affect the incidence of human brucellosis?
Conclusion
The study reveals a statistically significant decline in the incidence of human brucellosis after the vaccination programme.
Supporting Evidence
- The incidence rate of human brucellosis fell from 10.3 per 1,000 population to 0.3 per 1,000 after vaccination.
- Health education efforts contributed to a decline in human brucellosis incidence even among unvaccinated herds.
- Statistically significant reductions were observed in both vaccinated and unvaccinated populations.
Takeaway
Vaccinating animals and educating people can help reduce the number of humans getting sick from brucellosis.
Methodology
The study compared incidence rates of human brucellosis before and after a vaccination programme in two time periods.
Limitations
The study did not perform brucella cultivation for diagnosis.
Participant Demographics
Participants included 123 patients diagnosed with brucellosis and 274 matched controls from the same region.
Statistical Information
P-Value
< 0.001
Confidence Interval
0.10 – 0.23
Statistical Significance
p < 0.001
Digital Object Identifier (DOI)
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