Ethyl 3,3,3-trifluoro-2-hydroxy-2-(5-methoxy-1H-indol-3-yl)propionate
2011
Study of Ethyl 3,3,3-trifluoro-2-hydroxy-2-(5-methoxy-1H-indol-3-yl)propionate
publication
Evidence: moderate
Author Information
Author(s): Kadirova Zukhra, Tolipov Samat, Fedorovskiy Oleg, Bakhtiyar Ibragimov, Parpiev Nusrat
Primary Institution: Tashkent Chemical–Technological Institute
Hypothesis
The study aims to synthesize and analyze the crystal structure of a new trifluoropyruvate derivative of indole.
Conclusion
The synthesized compound forms a two-dimensional network structure through hydrogen bonding.
Supporting Evidence
- The compound crystallizes as a racemate with specific torsion angles.
- Molecules form inversion-related dimers via hydrogen bonds.
- The study provides insights into the unique properties of trifluoromethyl groups.
Takeaway
The researchers made a new chemical compound that can help create new medicines, and they figured out how its molecules are arranged.
Methodology
The compound was synthesized through a reaction of ethyl 3,3,3-trifluoropyruvate and 5-methoxyindole, followed by crystallization and X-ray diffraction analysis.
Digital Object Identifier (DOI)
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