An intense 18F-FDG pulmonary microfocus on PET without detectable abnormality on CT: A manifestation of an iatrogenic FDG pulmonary embolus
2010

Intense FDG Pulmonary Microfocus on PET without CT Abnormality

Sample size: 1 publication Evidence: low

Author Information

Author(s): Fathinul Fikri AS, Lau WFE

Primary Institution: Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Malaysia

Hypothesis

An intense 18F-FDG focus in the lungs without corresponding CT lesions may indicate an iatrogenic FDG microembolus.

Conclusion

The study highlights that an intense 18F-FDG-PET pulmonary abnormality without detectable lesions on CT is likely an artefact from FDG microembolus.

Supporting Evidence

  • An intense 18F-FDG focus was observed in the left lower lobe without a corresponding CT lesion.
  • The abnormality resolved completely on follow-up imaging seven months later.
  • FDG microembolus is suggested as the cause of the observed PET abnormality.

Takeaway

Sometimes, a scan can show something that looks like a problem, but it might just be a mistake from the injection. This study shows that in one case, the problem went away on its own.

Methodology

Case report of a 61-year-old woman with a history of breast cancer who underwent PET/CT imaging.

Potential Biases

Potential for misinterpretation of PET/CT results due to artefacts.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

61-year-old female with a history of breast carcinoma.

Digital Object Identifier (DOI)

10.2349/biij.6.4.e37

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