MannDB – A microbial database of automated protein sequence analyses and evidence integration for protein characterization
2006

MannDB: A Microbial Database for Protein Sequence Analysis

publication Evidence: high

Author Information

Author(s): Zhou Carol L, Ecale Marisa W, Smith Jason R, Zemla Adam T, Dyer Matthew D, Kuczmarski Thomas A, Vitalis Elizabeth A, Slezak Thomas R

Primary Institution: Lawrence Livermore National Laboratory

Hypothesis

MannDB was created to support the selection of proteins suitable for pathogen detection.

Conclusion

MannDB provides comprehensive protein sequence analyses for high-priority bio-threat organisms.

Supporting Evidence

  • MannDB organizes data from high-throughput protein-sequence analyses.
  • It includes predictions of various protein properties and features.
  • MannDB is linked to MvirDB for additional microbial virulence factor data.
  • The database is updated regularly to ensure current data is used.
  • Users can access a web client for viewing results and conducting searches.

Takeaway

MannDB is like a big library that helps scientists find important proteins to detect germs and toxins quickly.

Methodology

MannDB uses automated, high-throughput protein-sequence analyses and integrates data from various open-source tools.

Limitations

The software that populates and updates MannDB is not open-source.

Digital Object Identifier (DOI)

10.1186/1471-2105-7-459

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