A new shape for an old function: lasting effect of a physiologic surgical restoration of the left ventricle
2006

Surgical Restoration of the Left Ventricle

Sample size: 12 publication Evidence: moderate

Author Information

Author(s): Cirillo Marco, Amaducci Andrea, Villa Emmanuel, Tomba Margherita Dalla, Brunelli Federico, Mhagna Zen, Troise Giovanni, Quaini Eugenio

Primary Institution: Poliambulanza Foundation Hospital, Brescia, Italy

Hypothesis

Surgical restoration obtained with a particular shape of endoventricular patch leads to steady morphofunctional ventricular improvement.

Conclusion

Surgical restoration of the left ventricle can lead to lasting improvements in heart function and geometry.

Supporting Evidence

  • All patients were in NYHA class 1 at follow-up.
  • Ventricular changes showed significant improvement compared to preoperative values.
  • Ten patients showed normalized end-systolic volume index at follow-up.

Takeaway

Doctors can fix a part of the heart to help it work better after damage, and this can help people feel better for a long time.

Methodology

The study involved 12 patients who underwent left ventricular reconstruction and coronary revascularization, with echocardiographic evaluations at multiple time points.

Limitations

The study had a small sample size and lacked a control group.

Participant Demographics

All participants were male, with an average age of 66 years.

Statistical Information

P-Value

p = 0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1749-8090-1-40

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication