HPV Type Distribution in Cervical Cancer in Sichuan, China
Author Information
Author(s): Wu En-qi, Zhang Guo-nan, Yu Xiang-hui, Ren Yuan, Fan Ying, Wu Yong-ge, Kong Wei, Zha Xiao
Primary Institution: College of Life Science, Jilin University
Hypothesis
What is the distribution of high-risk HPV types in cervical cancer patients in Sichuan province, China?
Conclusion
HPV types 58, 52, and 59 are more prevalent than HPV18 in women with cervical cancer in Sichuan, China.
Supporting Evidence
- The overall HPV prevalence was 93.2% in the studied specimens.
- HPV16 was found to be the most prevalent type at 58.4%.
- The detection rates of HPV types increased significantly with Nested TS-PCR.
Takeaway
This study found that many women with cervical cancer in Sichuan have infections from certain types of HPV, especially types 16, 52, 58, and 59.
Methodology
The study used MY09/11 PCR, One-step TS PCR, and Nested TS PCR to detect HPV in cervical cancer specimens.
Limitations
The study may not represent HPV distribution in other regions of China.
Participant Demographics
Patients ranged in age from 17 to 71 years, with a mean age of 46 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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