A green replacement route to produce phosphatidylserine in environmentally friendly edible oil–water systems and investigations on the enzymatic mechanism
2024

Eco-Friendly Production of Phosphatidylserine Using Edible Oils

publication Evidence: high

Author Information

Author(s): Zhang Tiantian, Lan Haizhi, Wang Huan, Li Binglin, Gand Martin, Wang Jiao

Primary Institution: Institute of Food Chemistry and Food Biotechnology, Justus Liebig University Giessen

Hypothesis

Can phosphatidylserine be efficiently produced in environmentally friendly oil-water systems without toxic solvents?

Conclusion

The study successfully demonstrated that phosphatidylserine can be produced with over 93% yield using coconut and olive oil-water systems, avoiding toxic organic solvents.

Supporting Evidence

  • Phosphatidylserine is important for brain health and can be produced from soybean dregs.
  • Using coconut and olive oils resulted in higher yields of phosphatidylserine compared to traditional methods.
  • The study avoided toxic organic solvents entirely during the production process.

Takeaway

This study found a way to make a brain-healthy ingredient called phosphatidylserine using safe cooking oils instead of harmful chemicals.

Methodology

The study used phospholipase D-mediated transphosphatidylation in various edible oil-water systems to produce phosphatidylserine and employed molecular dynamics simulations to analyze the enzymatic mechanism.

Limitations

The study did not explore the long-term stability of the produced phosphatidylserine or its effects in real food systems.

Digital Object Identifier (DOI)

10.1111/1750-3841.17544

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