Rational Prescribing in Primary Care (RaPP): A Cluster Randomized Trial of a Tailored Intervention
2006

Improving Prescribing Practices in Primary Care

Sample size: 146 publication Evidence: moderate

Author Information

Author(s): Chris Del Mar

Primary Institution: Bond University

Hypothesis

Can a multicomponent intervention improve the prescribing of antihypertensive and cholesterol-lowering drugs in primary care?

Conclusion

The intervention modestly improved prescribing practices but was cost-effective and should be implemented widely.

Supporting Evidence

  • The intervention led to a 12% increase in prescribing thiazide diuretics.
  • The study found that despite the intervention, doctors did not significantly change their risk assessment practices.
  • The economic analysis showed that the costs of the intervention would be outweighed by savings within two years.

Takeaway

Doctors were encouraged to prescribe a specific type of medicine more often, but it didn't change much overall. However, it ended up saving money in the long run.

Methodology

A cluster-randomized controlled trial with educational outreach, audit and feedback, and computerized reminders.

Potential Biases

Doctors may be influenced more by drug advertisements than by guidelines.

Limitations

The intervention had no significant impact on major outcomes related to cardiovascular risk assessment.

Participant Demographics

General practices from two geographical areas.

Digital Object Identifier (DOI)

10.1371/journal.pmed.0030229

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