Deviant Peer Affiliation, Depression, and Adolescent Non-Suicidal Self-Injury: The Moderating Effect of the OXTR Gene rs53576 Polymorphism
2024

The Impact of Peer Influence and Genetics on Adolescent Self-Injury

Sample size: 469 publication 10 minutes Evidence: moderate

Author Information

Author(s): Li Jingjing, Yu Chengfu

Primary Institution: Guangzhou Medical University

Hypothesis

The influence of deviant peer affiliation on adolescent NSSI will be mediated by depression.

Conclusion

Depression serves as a link between deviant peer affiliation and non-suicidal self-injury in adolescents, particularly for those with the AA genotype of the OXTR gene rs53576.

Supporting Evidence

  • Deviant peer affiliation significantly affected depression.
  • Depression positively affected non-suicidal self-injury.
  • The indirect connection between peer influence and self-injury was significant for adolescents with the AA genotype.

Takeaway

If kids hang out with friends who do bad things, they might feel sad and hurt themselves, especially if they have a certain gene.

Methodology

The study used structural equation modeling analysis to verify a moderated mediation model with 469 adolescents completing questionnaires.

Potential Biases

The study's cross-sectional design may not capture the dynamic nature of NSSI development over time.

Limitations

The study focused only on middle school students, limiting the generalizability of the findings.

Participant Demographics

Participants were 469 adolescents aged 11 to 15 years, with 92.1% from two-parent households.

Statistical Information

P-Value

p<0.001

Confidence Interval

[0.15, 0.33]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/children11121445

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication