The Influence of Carbon-Carbon Multiple Bonds on the Solvolyses of Tertiary Alkyl Halides: a Grunwald-Winstein Analysis
2008

Influence of Carbon-Carbon Bonds on Solvolysis of Alkyl Halides

publication Evidence: moderate

Author Information

Author(s): Marina C. Reis, Ruben Elvas-Leitão, Filomena Martins

Primary Institution: University of Lisbon

Hypothesis

How do carbon-carbon multiple bonds affect the solvolysis rates of tertiary alkyl halides?

Conclusion

The study found unexpected negative sensitivity in the solvolysis rates of certain alkyl halides, suggesting a complex interaction between solvent and substrate.

Supporting Evidence

  • The study utilized the Grunwald-Winstein equation to analyze solvolysis rates.
  • Unexpected negative sensitivity was observed in certain alkyl halides.
  • The research highlights the complexity of solvent-substrate interactions.

Takeaway

This study looks at how certain chemical bonds change the way some compounds react with solvents, which helps us understand chemical reactions better.

Methodology

The extended Grunwald-Winstein equation was used to analyze the solvolysis of various tertiary alkyl halides in different solvent mixtures.

Potential Biases

Potential biases may arise from the choice of solvents and the interpretation of statistical data.

Limitations

The study's findings may not apply universally due to the specific conditions and substrates used.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ijms9091704

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