Effect of Coenzyme Q10 Supplementation on Lipid and Glycaemic Profiles: An Umbrella Review
2024

Effect of Coenzyme Q10 on Lipid and Blood Sugar Levels

Sample size: 2424 publication 10 minutes Evidence: moderate

Author Information

Author(s): Patiño-Cardona Silvana, Garrido-Miguel Miriam, Pascual-Morena Carlos, Berlanga-Macías Carlos, Lucerón-Lucas-Torres Maribel, Alfaro-González Sofía, Martínez-García Irene

Primary Institution: Universidad de Castilla-La Mancha

Hypothesis

Does Coenzyme Q10 supplementation improve lipid and glycaemic profiles?

Conclusion

Coenzyme Q10 supplementation may improve blood sugar levels and has some effect on lipid profiles, particularly in people with diabetes.

Supporting Evidence

  • CoQ10 showed a significant effect on fasting blood glucose levels.
  • Supplementation may reduce HbA1c levels in individuals with diabetes.
  • Some studies indicated improvements in total cholesterol and triglycerides.

Takeaway

Taking Coenzyme Q10 might help people with diabetes lower their blood sugar and improve their cholesterol levels.

Methodology

A systematic review and meta-analysis of studies evaluating CoQ10 supplementation effects on lipid and glycaemic profiles.

Potential Biases

High risk of bias due to inconsistent reporting and methodological issues in included studies.

Limitations

Many studies had low quality, and some did not adequately report on the usual treatments participants were taking.

Participant Demographics

Participants were mostly adults, with some studies including older individuals up to 89 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/jcdd11120377

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