Role of Human Milk Microbiota in Infant Neurodevelopment: Mechanisms and Clinical Implications
2024

The Role of Human Milk Microbiota in Infant Neurodevelopment

Sample size: 104 publication Evidence: moderate

Author Information

Author(s): Biagioli Valentina, Sortino Vincenzo, Falsaperla Raffaele, Striano Pasquale

Primary Institution: University of Genoa

Hypothesis

How does human milk microbiota influence infant neurodevelopment?

Conclusion

Human milk plays a crucial role in modulating the microbiota and supporting neurodevelopment in newborns.

Supporting Evidence

  • Human milk oligosaccharides (HMOs) have immunomodulatory and neurodevelopmental effects.
  • Breastfeeding can reduce the risk of necrotizing enterocolitis in preterm infants.
  • Studies show that the intake of HMOs improves learning and memory in animal models.

Takeaway

Breast milk is super important for babies because it helps their brains grow and keeps them healthy by providing good bacteria.

Methodology

The study reviewed literature from 2013 to 2024 using databases like Web Science, PubMed, and Scopus, focusing on human milk and its effects on infant health.

Limitations

Further longitudinal studies and randomized control trials are needed to fully understand the clinical outcomes of bioactive components in human milk.

Statistical Information

P-Value

p = 0.005

Digital Object Identifier (DOI)

10.3390/children11121476

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