Homoeologous gene silencing in tissue cultured wheat callus
2008

Homoeologous Gene Silencing in Wheat Callus

publication Evidence: moderate

Author Information

Author(s): Andrew Bottley, Natalie Chapman, Robert Koebner

Primary Institution: University of Nottingham

Hypothesis

Does the frequency of homoeologous silencing in in vitro cultured wheat callus differ from that in differentiated organs?

Conclusion

The study suggests that homoeologous silencing in differentiated tissues is likely controlled by epigenetic factors rather than genomic instability.

Supporting Evidence

  • Homoeologous gene silencing can be tissue specific and linked to developmental or stress responses.
  • In vitro cultured wheat callus showed no silencing in the tested genes.
  • The study reinforces the idea of plasticity in the wheat epi-genome.

Takeaway

This study found that when wheat cells are grown in a lab, they don't silence certain genes like they do in normal plant tissues, which might be because of differences in how their DNA is organized.

Methodology

The study used reverse transcription PCR and single strand conformation polymorphism to analyze gene expression in wheat callus tissue.

Digital Object Identifier (DOI)

10.1186/1471-2156-9-65

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