Effectiveness of the Standard WHO Recommended Retreatment Regimen (Category II) for Tuberculosis in Kampala, Uganda: A Prospective Cohort Study
2011

Ethical Challenges in TB Research in Uganda

publication Evidence: moderate

Author Information

Author(s): Jerome Amir Singh

Primary Institution: Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of Kwazulu-Natal

Conclusion

The Uganda study has addressed an important knowledge gap and catalyzed the provision of second-line TB therapy, leaving the local population better off.

Supporting Evidence

  • The Uganda study highlights ethical issues in conducting research where standard care is lacking.
  • Investigators provided second-line treatment regimens to participants diagnosed with MDR-TB.
  • The study aims to inspire policy reform in TB treatment in Uganda.

Takeaway

The study shows that even in places with limited resources, researchers can help improve health care by providing better treatments while studying diseases.

Digital Object Identifier (DOI)

10.1371/journal.pmed.1000421

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