Factors Affecting Non-sentinel Lymph Node Metastasis in Early-Stage Breast Cancer
Author Information
Author(s): Muacevic Alexander, Adler John R, Demircioğlu Zeynep Gül, Demircioğlu Mahmut Kaan, Tanık Canan T, Yetkin Sitki Gurkan
Primary Institution: Sisli Hamidiye Etfal Training and Research Hospital
Hypothesis
What factors affect non-sentinel lymph node metastasis in patients with early-stage clinically node-negative breast cancer?
Conclusion
Cerb-B2-positive patients are more likely to have axillary non-sentinel lymph node metastasis, especially as the cancer stage progresses.
Supporting Evidence
- The mean age of patients was 52.6 years.
- 50.7% of patients had no metastasis in non-sentinel lymph nodes.
- The study found a significant correlation between Cerb-B2 positivity and non-sentinel lymph node metastasis.
Takeaway
This study found that some patients with early-stage breast cancer might not need extensive surgery if they have certain characteristics, like being Cerb-B2 positive.
Methodology
Data from 65 female patients were analyzed retrospectively, focusing on various tumor and patient characteristics.
Limitations
The study may have a limited number of patients due to the decreasing frequency of axillary dissection surgeries.
Participant Demographics
All participants were female patients with early-stage breast cancer.
Statistical Information
P-Value
p=0.046
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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