ABO Blood Groups and Placental Malaria in Eastern Sudan
Author Information
Author(s): Adam Ishag, Babiker Saud, Mohmmed Ahmed A, Salih Magdi M, Prins Martin H, Zaki Zaki M
Primary Institution: Department of Obstetrics & Gynecology, Faculty of Medicine University of Khartoum, Sudan
Hypothesis
The study aimed to investigate the role of ABO blood groups on pregnancy outcomes in an area of unstable malaria transmission in eastern Sudan.
Conclusion
Women of eastern Sudan are at risk for placental malaria infection irrespective of their age or parity, with those having blood group O at higher risk of past placental malaria infection.
Supporting Evidence
- 114 (39.7%) women were primiparae, 61 (22.1%) were secundiparae, and 118 (38.2%) were multiparae.
- 82 (28.0%) of the placentae showed past infection and 199 (68.0%) showed no infection.
- Women with blood group O were at higher risk for past placental infections (OR = 1.9).
- Maternal haemoglobin was significantly higher in women with blood group O.
Takeaway
This study found that pregnant women in eastern Sudan can get malaria in their placenta, and those with blood type O are more likely to have had past infections.
Methodology
The study analyzed 293 women delivering at New Half teaching hospital, determining ABO blood groups and performing placental histopathology examinations for malaria.
Potential Biases
Potential selection bias as only women with singleton deliveries were included.
Limitations
The study was conducted in a single hospital and may not represent all areas of eastern Sudan.
Participant Demographics
The mean age of participants was 25.6 years, with 19.4% being teenagers (age ≤ 19 years).
Statistical Information
P-Value
0.01
Confidence Interval
95% CI = 1.1–3.2
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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