Antibiotic Susceptibility of Brucella melitensis
Author Information
Author(s): Turkmani Aun, Ioannidis Alexandros, Christidou Athanasia, Psaroulaki Anna, Loukaides Feidias, Tselentis Yiannis
Primary Institution: University of Crete, Greece
Hypothesis
What is the antibiotic susceptibility profile of Brucella melitensis isolates from the eastern Mediterranean?
Conclusion
Brucella isolates remain susceptible in vitro to most antibiotics used for treatment of brucellosis.
Supporting Evidence
- All isolates were susceptible to tetracycline, streptomycin, gentamicin, ciprofloxacin, norfloxacin, and levofloxacin.
- Two isolates showed reduced susceptibility to rifampicin and eight to trimethoprim/sulfamethoxazole.
- Erythromycin had the highest MIC90 value among the tested antibiotics.
Takeaway
This study tested how well Brucella bacteria from sick people and animals respond to different antibiotics, and found that most of them still work well.
Methodology
The study tested the antibiotic susceptibilities of 74 Brucella melitensis isolates using the E-test method.
Limitations
There is no standardized method for susceptibility testing recommended for Brucella species.
Participant Demographics
Isolates were from human patients and animals in Crete, Cyprus, and Syria.
Digital Object Identifier (DOI)
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