Irvingia gabonensis fat: nutritional properties and effect of increasing amounts on the growth and lipid metabolism of young rats
2011

Effects of Dika Nut Fat on Young Rats

Sample size: 40 publication 10 minutes Evidence: moderate

Author Information

Author(s): Nangue Thierry Joël, Womeni Hilaire Macaire, Mbiapo Felicite Tchouanguep, Fanni Jacques, Michel Linder

Primary Institution: University of Dschang, Cameroon

Hypothesis

Dika nut fat has no undesirable effects on the plasma cholesterol of rats.

Conclusion

Increasing amounts of dika nut fat significantly alter cholesterol and triglyceride levels, while also increasing HDL-cholesterol.

Supporting Evidence

  • The study found a significant increase in serum cholesterol and triglycerides in high fat groups.
  • Weight of vital organs did not vary much, except for a significant reduction in liver weight in males.
  • HDL-cholesterol levels increased significantly with higher dika nut fat intake.

Takeaway

This study shows that feeding young rats dika nut fat can change their cholesterol levels, making some types of cholesterol go up.

Methodology

Young rats were fed diets with varying amounts of dika nut fat for three weeks, and their growth and lipid metabolism were analyzed.

Limitations

The study was limited to a short duration and a specific animal model.

Participant Demographics

Young Wistar rats, both male and female.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1476-511X-10-43

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