Tic62: a protein family from metabolism to protein translocation
2007
Tic62: A Protein Family from Metabolism to Protein Translocation
publication
Evidence: moderate
Author Information
Author(s): Balsera Mónica, Stengel Anna, Soll Jürgen, Bölter Bettina
Primary Institution: Dep Biologie I, Botanisches Institut, LMU München, Germany
Hypothesis
Tic62 may act as a redox sensor protein and regulator during the translocation process in chloroplasts.
Conclusion
The Tic62-NAD(P)-related proteins are of ancient origin and the FNR-binding module in vascular plants is likely essential for the protein's function.
Supporting Evidence
- The N-terminal module of Tic62 is highly conserved among all oxyphototrophs.
- The C-terminal region is only found in vascular plants.
- Phylogenetic analyses classify four Tic62-NAD(P)-related protein subfamilies in land plants.
- Tic62 proteins are likely involved in the import process into chloroplasts.
Takeaway
Tic62 is a protein that helps transport other proteins into chloroplasts, and it has been around for a long time, found in both ancient bacteria and modern plants.
Methodology
The study involved evolutionary analysis and sequence comparison of the Tic62-NAD(P)-related protein family.
Digital Object Identifier (DOI)
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