Spectral Domain Optical Coherence Tomography in Diffuse Unilateral Subacute Neuroretinitis
2011

SD-OCT Findings in Diffuse Unilateral Subacute Neuroretinitis

Sample size: 8 publication Evidence: moderate

Author Information

Author(s): Garcia Filho Carlos Alexandre de A., Soares Ana Claudia Medeiros de A. G., Penha Fernando Marcondes, Garcia Carlos Alexandre de Amorim

Primary Institution: Universidade Federal do Rio Grande do Norte

Hypothesis

To describe SD-OCT findings in patients with diffuse unilateral subacute neuroretinitis and evaluate CRT and RNFL thickness.

Conclusion

RNFL and CMT were thinner in DUSN eyes compared to normal eyes, with more pronounced thinning in late-stage disease.

Supporting Evidence

  • Mean RNFL thickness was 80.25 μm for affected eyes and 104.75 μm for normal eyes.
  • Mean CMT was 205.5 μm for affected eyes and 255.13 μm for normal fellow eyes.
  • Late-stage disease had mean RNFL thickness of 74.83 μm compared to 96.5 μm in early stage.

Takeaway

This study looked at patients with a specific eye disease and found that their eye layers were thinner than normal, especially in those with more severe disease.

Methodology

Retrospective study reviewing medical records of patients diagnosed with DUSN who underwent SD-OCT.

Limitations

Small sample size and lack of statistical analysis for early-stage disease due to few patients.

Participant Demographics

Mean age of affected patients was 17 years, with 7 out of 8 patients being male.

Statistical Information

P-Value

0.0005

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/285296

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication