Management of Cardiac Involvement in NeuroMuscular Diseases: Review
2008

Management of Cardiac Involvement in Neuromuscular Diseases

publication Evidence: moderate

Author Information

Author(s): Rachida Bouhouch, Tarik Elhouari, Latifa Oukerraj, Ibtissam Fellat, Jamila Zarzur, Rajaa Bennani, Mhamed Arharbi

Primary Institution: Service de Cardiologie B, CHU Ibn Sina Rabat, MAROC

Hypothesis

Preventive therapy is recommended for cardiac involvement in common neuromuscular diseases.

Conclusion

Close surveillance and early initiation of preventive therapy can improve outcomes in patients with cardiac involvement in neuromuscular diseases.

Supporting Evidence

  • Preventive therapy with beta-blockers and ACE inhibitors is recommended for Duchenne and Myotonic Dystrophy.
  • Duchenne Muscular Dystrophy has a high risk of sudden cardiac death, necessitating close cardiac monitoring.
  • Early initiation of ACE inhibitors has been associated with lower mortality in patients with Duchenne Muscular Dystrophy.

Takeaway

Some muscle diseases can affect the heart, so doctors need to check the heart closely and start treatment early to help patients live longer.

Methodology

Review of existing literature on cardiac involvement in neuromuscular diseases and recommendations for management.

Limitations

Little is known about managing cardiac complications in children with these diseases.

Digital Object Identifier (DOI)

10.2174/1874192400802010093

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