Comparing Imaging Techniques for Gadolinium Distribution in the Heart
Author Information
Author(s): Michael Salerno, Patrick Antkowiak, John J Green, Rajesh Janardhanan, Ronny A Jiji, Christopher M Kramer, Frederick H Epstein
Primary Institution: University of Virginia, Charlottesville, VA, USA
Hypothesis
First-pass contrast-enhanced imaging provides different results for gadolinium distribution compared to T1 mapping.
Conclusion
First-pass contrast-enhanced and T1 mapping techniques provide similar measures of gadolinium distribution volume in normal subjects, but each has specific advantages.
Supporting Evidence
- The mean Ktrans from first-pass data was 0.41±0.02.
- The mean Vd was higher from the first-pass technique (0.34±0.05) compared to T1 mapping (0.29±0.01).
Takeaway
The study looked at two ways to see how a dye spreads in the heart, and found they give similar results but have different strengths.
Methodology
Five healthy volunteers underwent first-pass contrast-enhanced imaging and T1 mapping to measure gadolinium distribution volume.
Limitations
The study was limited to a small sample size of healthy volunteers.
Participant Demographics
Healthy volunteers with an average age of 36 years.
Statistical Information
P-Value
0.02
Statistical Significance
p=0.02
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website