Minimal Breast Cancer Study
Author Information
Author(s): Dublin E A, Millis R R, Smith P, Bobrow L G
Primary Institution: Hedley Atkins/ICRF Breast Pathology Laboratory, Guy's Hospital
Hypothesis
Can minimal breast cancers be classified into distinct groups based on histology and biological marker expression?
Conclusion
The study found significant differences in histology and marker expression between different groups of minimal breast cancers, suggesting they may require different treatment approaches.
Supporting Evidence
- The study identified three groups of minimal breast cancers based on histology.
- Significant differences were found in the extent of invasion and tumor grade between the invasive groups.
- Marker expression varied significantly between the predominant invasive and predominant DCIS groups.
Takeaway
The researchers looked at 98 cases of minimal breast cancer and found that they can be grouped in different ways, which might help doctors choose better treatments.
Methodology
Histological and immunohistochemical analysis of breast cancer samples.
Participant Demographics
Patients diagnosed with minimal breast cancer between 1975 and 1990.
Statistical Information
P-Value
P < 0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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