The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050
2005

Predicted Mesothelioma Deaths in Great Britain

Sample size: 90000 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hodgson J T, McElvenny D M, Darnton A J, Price M J, Peto J

Primary Institution: Epidemiology and Medical Statistics Unit, Health and Safety Executive

Hypothesis

What will be the future burden of mesothelioma mortality in Great Britain from 2002 to 2050?

Conclusion

The study predicts that mesothelioma mortality in Great Britain will peak at around 1950 to 2450 deaths per year between 2011 and 2015, with approximately 90,000 deaths expected by 2050.

Supporting Evidence

  • The annual number of mesothelioma deaths in Great Britain has risen from 153 in 1968 to 1848 in 2001.
  • The model predicts that there will be approximately 90,000 deaths from mesothelioma in Great Britain by 2050.
  • The majority of mesothelioma deaths occur among men aged 60-79 years.

Takeaway

This study looks at how many people will die from a type of cancer caused by asbestos in the UK over the next few decades, predicting a big peak in deaths before they start to go down.

Methodology

Poisson regression analysis was used to model male mesothelioma deaths from 1968 to 2001 based on asbestos exposure.

Potential Biases

The model may not account for background rates of mesothelioma not related to asbestos exposure.

Limitations

The model's predictions are uncertain and depend on assumptions about future asbestos exposure levels.

Participant Demographics

The study focused on male mesothelioma deaths in Great Britain, particularly among those aged 20-89 years.

Statistical Information

P-Value

0.0022

Confidence Interval

95% CI 1650–2100

Statistical Significance

p=0.0022

Digital Object Identifier (DOI)

10.1038/sj.bjc.6602307

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication