Hydrogel from Jania rubens to Fight Candida tropicalis
Author Information
Author(s): Boran Meltem, Eliuz Elif Erdogan, Ayas Deniz
Primary Institution: Mersin University
Hypothesis
The study aimed to create a bioactive hydrogel using Jania rubens extracts to investigate its anti-candidal properties against Candida tropicalis.
Conclusion
The Jania rubens/PVA/PVP hydrogel demonstrated significant anti-candidal activity against Candida tropicalis, especially within the first 5 minutes of exposure.
Supporting Evidence
- The hydrogel showed an inhibition zone of 9.01 mm against Candida tropicalis.
- The minimum inhibitory concentration (MIC) was determined to be 80.20 mg/mL.
- Logarithmic reduction of viable cells was 1.5 CFU/mL after 5 minutes of exposure.
Takeaway
Researchers made a special gel from red algae that can help fight a type of fungus that can make people sick.
Methodology
The hydrogel was prepared using PVA/PVP and Jania rubens extracts, followed by testing its anti-candidal activity through disc diffusion and minimum inhibitory concentration methods.
Limitations
The study did not explore the long-term effects or in vivo applications of the hydrogel.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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