Factors Associated with Inadequate Tissue Yield in EUS-FNA for Gastric SMT
2011

Factors Affecting Tissue Yield in EUS-FNA for Gastric Tumors

Sample size: 47 publication Evidence: moderate

Author Information

Author(s): Suzuki Takuto, Arai Makoto, Matsumura Tomoaki, Arai Eiji, Hata Sachio, Maruoka Daisuke, Tanaka Takeshi, Nakamoto Shingo, Imazeki Fumio, Yokosuka Osamu

Primary Institution: Chiba University Hospital

Hypothesis

What factors contribute to inadequate tissue yield in EUS-FNA biopsies of gastric submucosal tumors?

Conclusion

Younger age and the location of the lesion in the lower third of the stomach are associated with inadequate tissue yield in EUS-FNA biopsies.

Supporting Evidence

  • The diagnostic yield of EUS-FNA for gastric SMTs was found to be 74.5%.
  • Patients under 60 years had a significantly lower diagnostic yield.
  • Lesions located in the lower third of the stomach were more likely to yield inadequate tissue.

Takeaway

Doctors found that younger patients and those with tumors in the lower part of the stomach had a harder time getting enough tissue for testing during a special biopsy.

Methodology

The study involved 47 patients who underwent EUS-FNA for suspected gastric submucosal tumors, evaluating various factors retrospectively.

Potential Biases

Potential bias due to the study being retrospective and conducted at one hospital.

Limitations

The study was conducted at a single institution, which may limit the generalizability of the findings.

Participant Demographics

24 males and 23 females, mean age 60.4 years (range 39–81 years).

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI = 1.761–80.48 for age; 95% CI = 1.290–87.42 for location.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.5402/2011/619128

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