Transdermal opioids for cancer pain
2006

Transdermal Opioids for Cancer Pain

Sample size: 1828 publication 10 minutes Evidence: moderate

Author Information

Author(s): Skaer Tracy L

Primary Institution: College of Pharmacy, Washington State University

Hypothesis

Can transdermal opioids provide effective pain management for cancer patients?

Conclusion

Transdermal formulations of fentanyl and buprenorphine are effective for managing moderate to severe cancer pain, but dosing must be individualized to avoid undertreatment.

Supporting Evidence

  • Transdermal fentanyl is effective and well tolerated for cancer pain.
  • Many cancer patients are prescribed subtherapeutic doses of pain medications.
  • A more aggressive dosing algorithm is recommended for transdermal fentanyl.

Takeaway

This study shows that special patches can help cancer patients manage their pain better, but doctors need to be careful about how much they give.

Methodology

The study involved a review of literature and clinical experience regarding the use of transdermal opioids in cancer pain management.

Potential Biases

Potential bias in the selection of studies reviewed and the interpretation of results.

Limitations

The study may not account for all individual patient factors affecting pain management.

Participant Demographics

The study included cancer patients, with a focus on those experiencing moderate to severe pain.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7525-4-24

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