PCR-DGGE assessment of the bacterial diversity of breast milk in women with lactational infectious mastitis
2008

Bacterial Diversity in Breast Milk of Women with Mastitis

Sample size: 20 publication Evidence: moderate

Author Information

Author(s): Susana Delgado, Rebeca Arroyo, Rocío Martín, Juan M Rodríguez

Primary Institution: Universidad Complutense de Madrid

Hypothesis

Infectious mastitis may be the consequence of a disbiotic process leading to an overgrowth of certain bacterial species.

Conclusion

Staphylococci are the main etiological agents of human lactational mastitis, indicating a disbiotic process in breast milk.

Supporting Evidence

  • Staphylococci were the dominant bacterial group in the milk samples.
  • S. epidermidis was the most frequently isolated species.
  • The study combined culture and molecular techniques for better bacterial characterization.
  • Lactic acid bacteria were detected by PCR-DGGE but not isolated from the samples.

Takeaway

This study found that certain bacteria, especially staphylococci, can grow too much in the milk of women with mastitis, which can make breastfeeding harder.

Methodology

Breast milk samples were analyzed using culture-dependent and culture-independent methods, including PCR-DGGE.

Limitations

The study did not isolate lactic acid bacteria from the samples, which may indicate their non-viability due to overgrowth of mastitis-causing agents.

Participant Demographics

Women aged 26–34 years with clinical symptoms of infectious mastitis.

Digital Object Identifier (DOI)

10.1186/1471-2334-8-51

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