Defining the relationship between gastroesophageal reflux and cough: probabilities, possibilities and limitations
2007

Understanding the Link Between Cough and Gastroesophageal Reflux

Commentary Evidence: low

Author Information

Author(s): Matthew M Eastburn, Peter H Katelaris, Anne B Chang

Hypothesis

Is there a true difference in the association between gastroesophageal reflux disease (GORD) and chronic cough, or do differing opinions stem from varying perspectives in respiratory and gastroenterology fields?

Conclusion

While cough and GORD often coexist, determining a direct cause-and-effect relationship remains challenging due to various factors.

Supporting Evidence

  • Cough and GORD commonly coexist in both children and adults.
  • Chronic cough is associated with significant morbidity and economic costs.
  • There is a lack of published randomized trials on the relationship between cough and GORD.

Takeaway

Cough and reflux can happen together, but it's hard to tell if one causes the other. Doctors have different opinions on this.

Potential Biases

Differences in opinions between respiratory and gastroenterology societies may lead to biased guidelines.

Limitations

The commentary discusses the lack of randomized controlled trials and the challenges in measuring the relationship between cough and GORD.

Digital Object Identifier (DOI)

10.1186/1745-9974-3-4

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