A New Spectrophotometric Method for Determination of Selenium in Cosmetic and Pharmaceutical Preparations after Preconcentration with Cloud Point Extraction
2011

New Method to Measure Selenium in Cosmetics and Pharmaceuticals

publication Evidence: moderate

Author Information

Author(s): Mohammad Hosein Soruraddin, Heydari Rouhollah, Puladvand Morteza, Zahedi Mir Mehdi

Primary Institution: Tabriz University

Hypothesis

Can a new spectrophotometric method accurately determine trace amounts of selenium in cosmetic and pharmaceutical products?

Conclusion

The proposed method is simple, rapid, and effective for determining selenium in various samples.

Supporting Evidence

  • The method achieved a detection limit of 4.4 ng/mL for selenium.
  • The relative standard deviation for six replicate measurements was 2.18%.
  • The method was successfully applied to real samples including multivitamins and shampoo.

Takeaway

This study created a new way to find tiny amounts of selenium in shampoos and vitamins using a special chemical process.

Methodology

The method involves reducing selenium to selenium (IV) and using cloud point extraction for concentration before spectrophotometric measurement.

Limitations

The method may be affected by the presence of certain cations that interfere with selenium detection.

Digital Object Identifier (DOI)

10.1155/2011/729651

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