Extreme Heat Exposure and Epigenetic Aging Acceleration Among Older Adults in the US
2024
Extreme Heat and Aging in Older Adults
Sample size: 3414
publication
Evidence: high
Author Information
Author(s): Choi Eunyoung, Ailshire Jennifer
Primary Institution: University of Southern California
Hypothesis
This study examines the association between heat exposure and epigenetic aging among older adults.
Conclusion
Extreme heat exposure is linked to accelerated biological aging in older adults.
Supporting Evidence
- Acute heat exposure was significantly associated with increased Horvath, Hannum, and PhenoAge acceleration.
- Long-term heat exposure was associated with increased PhenoAge, GrimAge, and DunedinPACE.
Takeaway
Being in very hot weather can make older people age faster on a cellular level.
Methodology
The study used data from the Health and Retirement Study and assessed heat exposure using meteorological data linked to participants' locations.
Participant Demographics
US adults aged 50 or above
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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