An analysis of the subtypes of dengue fever infections in Barbados 2003–2007 by reverse transcriptase polymerase chain reaction
2008

Dengue Fever Subtypes in Barbados (2003-2007)

Sample size: 172 publication Evidence: moderate

Author Information

Author(s): Marquita Gittens-St Hilaire, Nicole Clarke-Greenidge

Primary Institution: University of the West Indies, Faculty of Medical Sciences

Hypothesis

To determine the serotypes of dengue virus present in Barbados using molecular techniques.

Conclusion

DENV-3 is currently circulating on the island and not DENV-1 or DENV-2 as in previous years.

Supporting Evidence

  • The study analyzed 172 patients diagnosed with dengue fever.
  • DENV-3 was found in over 99% of the cases.
  • Common symptoms included fever, headache, and arthralgia.

Takeaway

This study looked at dengue fever cases in Barbados and found that most infections were caused by a specific type of the virus called DENV-3.

Methodology

A retrospective analysis of patients with IgM antibodies to dengue fever infection was conducted, using reverse transcriptase polymerase chain reaction for serotyping.

Limitations

The study may not capture all cases of dengue fever due to reliance on IgM antibody detection.

Participant Demographics

The study included 71 males and 101 females, with ages ranging from 0 to 50+ years.

Digital Object Identifier (DOI)

10.1186/1743-422X-5-152

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