Factors Influencing Drug Prescribing for Patients With Hospitalization History in Circulatory Disease–Patient Severity, Composite Adherence, and Physician-Patient Relationship: Retrospective Cohort Study
2024

Factors Influencing Drug Prescribing for Patients With Hospitalization History in Circulatory Disease

Sample size: 48456 publication 10 minutes Evidence: moderate

Author Information

Author(s): Köttl Hanna, Balanescu Paul, Ateya Mohammad, Butt Muhammad Daoud, Takura Tomoyuki, Yokoi Hiroyoshi, Honda Asao

Primary Institution: Nihon University School of Medicine

Hypothesis

The study aimed to verify how patient severity, composite adherence, and physician-patient relationships impact the switch to generic drugs.

Conclusion

Improved patient condition and adherence are associated with increased generic drug switching, influenced by the physician-patient relationship.

Supporting Evidence

  • Generic drug rates increased with improvements in HbA1c levels.
  • Patients with a superior physician-patient relationship had a higher rate of generic drug prescribing.
  • Logistic regression analysis revealed significant associations between clinical parameters and generic drug switching.

Takeaway

Doctors are more likely to prescribe generic drugs if patients are healthier and have a good relationship with their doctor.

Methodology

A long-term retrospective cohort study analyzing data from a national health care database over four years.

Potential Biases

Potential bias due to the exclusion of samples with missing data and reliance on proxy indicators.

Limitations

The study did not deeply analyze individual drug characteristics and relied on proxy indicators for the physician-patient relationship.

Participant Demographics

The cohort predominantly included older adults, with an average age of 68.3 years and 61.9% male.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI 0.993-0.999

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.2196/59234

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