Survival from laryngeal cancer in England and Wales up to 2001
2008

Survival from Laryngeal Cancer in England and Wales

Sample size: 4000 publication Evidence: moderate

Author Information

Author(s): Nutting C M, Robinson M, Birchall M

Primary Institution: Royal Marsden Hospital

Hypothesis

Any increase in survival is more likely to devolve from those with advanced disease.

Conclusion

The observed improvements in survival for laryngeal cancer are likely real and multifactorial in origin.

Supporting Evidence

  • There was a statistically significant 12.6% improvement in 2-year survival between cohorts of patients in the south and west of England.
  • The cure rates for early-stage larynx cancer are already greater than 90%.
  • Improvements in accuracy of diagnosis and staging have certainly occurred.

Takeaway

Doctors have found that more people are surviving laryngeal cancer now than before, and this is likely due to better treatments and diagnosis.

Methodology

The study analyzed changes in survival rates and treatment practices for laryngeal cancer over a period from 1985 to 2001.

Potential Biases

The concentration of survival improvements in affluent groups suggests potential biases in access to care.

Limitations

The study may not identify specific changes in practice that caused survival improvements.

Participant Demographics

The study included head and neck cancer patients from different socio-economic backgrounds in England and Wales.

Statistical Information

P-Value

12.6%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604582

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