bZIPDB: A Database of Human bZIP Transcription Factors
Author Information
Author(s): Ryu Taewoo, Jung Juhyun, Lee Sunjae, Nam Ho Jung, Hong Sun Woo, Yoo Jae Wook, Lee Dong-ki, Lee Doheon
Primary Institution: Korea Advanced Institute of Science and Technology
Conclusion
bZIPDB is a valuable resource that provides extensive regulatory information for human bZIP transcription factors.
Supporting Evidence
- bZIPDB contains information on 49 human bZIP transcription factors.
- The database includes 721 protein interactions and 560 TF-target gene relationships.
- bZIPDB is updated annually with new information.
Takeaway
bZIPDB is like a big library that helps scientists understand how certain proteins work in our bodies, especially those that can affect diseases like cancer.
Methodology
The database was constructed using automated literature collection and manual curation, compiling data on protein interactions and gene relationships.
Limitations
The database relies on existing literature, which may not cover all interactions or regulatory mechanisms.
Digital Object Identifier (DOI)
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