Treatment of malignant pericardial effusion with 32P-colloid
1999

Treatment of malignant pericardial effusion with 32P-colloid

Sample size: 36 publication Evidence: high

Author Information

Author(s): Dempke W, Firusian N

Primary Institution: Department of Internal Medicine IV, Martin-Luther-University Halle-Wittenberg

Hypothesis

The study aims to evaluate the efficacy of intrapericardial 32P-colloid in terms of response rates and duration of remissions.

Conclusion

Intrapericardial instillation of 32P-colloid is a simple, reliable, and safe treatment strategy for patients with malignant pericardial effusions.

Supporting Evidence

  • Intrapericardial 32P-colloid resulted in a complete remission rate of 94.5% in patients.
  • The median duration of remission was 8 months.
  • No side effects were observed with the treatment.

Takeaway

Doctors can use a special treatment called 32P-colloid to help patients with a serious heart fluid problem, and it works really well.

Methodology

Intrapericardial instillation of 185–370 MBq (5–10 mCi) 32P-colloid was performed on patients with malignant pericardial effusion.

Limitations

Two patients did not respond to treatment due to rapid formation of pericardial fluid.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690625

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